Clinical Observer

Illustration: Gilead posts phase 3 results for bictegravir/lenacapavir
Illustration: Clinical Observer
Bictegravir/lenacapavir

Gilead posts phase 3 results for bictegravir/lenacapavir

At week 48, 0.8% of participants on the fixed-dose combination and 1.1% on a stable baseline regimen had HIV-1 RNA of at least 50 copies/mL, according to the registry posting.

Immuno Oncology
Photograph: GSK (press image)
Bepirovirsen approval

FDA approves bepirovirsen for chronic hepatitis B

In phase 3 trials, about one in five adults reached a functional cure after a six-month course, but a boxed warning requires close monitoring.

Entrance to Mass General Brigham Healthcare Center at Patriot Place in Foxborough, Massachusetts
Photograph: Kenneth C. Zirkel/Wikimedia Commons (CC BY-SA 4.0)
Mass General Brigham

Mass General Brigham cuts staff and halves Home Hospital

The Boston Globe reports the system will cut its Home Hospital program to no more than 30 patients, down from about 70 in 2024, while losing about $30 million a year.

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